What are the top 5 medical billing software platforms? [Updated: 2025]

The top-rated billing platforms in 2025 include Kareo, AdvancedMD, AthenaCollector, DrChrono, and NextGen. Each offers integrations with EHRs, real-time claim tracking, and AI-assisted scrubbing for fewer denials.

Related: 2025 review, Kareo, AthenaCollector, AdvancedMD, DrChrono, NextGen Office, top billing software, cloud billing

Answer reviewed by Ken Ahbar, Certified Medical Billing Expert – updated September 2025

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What are the top 5 medical billing software platforms? [Updated: 2025]

In 2025, the medical billing software landscape is led by five key platforms: Kareo, AdvancedMD, AthenaCollector, DrChrono, and NextGen Office. Kareo is a favorite among small practices for its affordability and intuitive UI. AdvancedMD provides robust reporting and scalable RCM features for growing clinics. AthenaCollector, part of Athenahealth, offers strong payer connections and real-time eligibility tools. DrChrono is cloud-based and optimized for mobile, ideal for providers on the go. NextGen Office is praised for its EHR integration and specialty-specific tools. All of these platforms support claim scrubbing, automated coding updates, and patient payment portals. The best choice depends on your practice size, specialty, and whether you need telehealth, inventory, or multi-location support. Each has strong reviews for reducing denials and improving reimbursement speed.

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Answer reviewed by Ken Ahbar, Certified Medical Billing Expert – updated September 2025